Lifelabs Panorama

Panorama™ NIPT is appropriate for singleton or twin pregnancies, as well as singleton pregnancies conceived using egg donors or surrogates. This test is not informative in pregnancies with 3 or more fetuses, nor for women who have had a bone marrow transplant or organ transplant.

Patient Pamphlet: https://www.lifelabsgenetics.com/wp-content/uploads/2018/02/Panorama-Patient-Brochure.pdf

Cost:

·         Basic Panel: $550 Trisomy 21, 18, 13, Monosomy X, sex chromosome trisomies, triploidy, complete molar pregnancy and fetal sex (optional)

·         Extended Panel: $745 Basic Prenatal Panel, plus 22q.11.2 [DiGeorge Syndrome]

·         Full Prenatal Panel: $795 Basic Prenatal Panel, plus 5 microdeletions (22q.11.2 [DiGeorge syndrome], 1p36 deletion syndrome, Angelman syndrome, Cri-du-chat syndrome, Prader-Willi syndrome)

Syndromes tested: Trisomy 21 ( Down Syndrome), Trisomy 18 (Edwards Syndrome), Trisomy 13 (Patau Syndrome), Monosomy X (Turner Syndrome), and sex chromosome trisomies.

Add-On Options: Fetal sex (no charge), extended/microdeletion panels (22q11.2 deletion/DiGeorge, Prader-Willi, Angelman, Cri-Du-Chat, 1p36 deletion)

Where to get it done: any Lifelabs location

How early it can be done: >9+0 weeks

Length of time for results: within 7-10 days of being received in the lab

Twins: Yes. Can tell you if twins are identical or fraternal, and report the sex of each fetus. For identical twins, can detect sex chromosome trisomies, monosomy X, and 22q11.2 deletion syndrome for each twin.

How to order: Ask your midwives for a requisition. You will also need to print and fill the payment form to accompany your requisition at the lab.

Payment Form: https://www.lifelabsgenetics.com/wp-content/uploads/2020/05/Panorama-Private-Pay-Paymt-Form.pdf

Genetic Counsellor contact: 1-84-GENE-HELP (1844-363-4357)

More info/FAQ: https://www.lifelabsgenetics.com/resources/faq/

Accuracy: https://www.lifelabsgenetics.com/wp-content/uploads/2020/11/Detail-Aid-Panorama.pdf

Dynacare Harmony

The Harmony NIPT can screen for genetic abnormalities even if twins are expected or if fertility treatment has been used including IVF (in vitro fertilization), donor sperm, or surrogacy. Patients with a twin pregnancy are not eligible for monosomy X, sex chromosome aneuploidy or 22q11.2 options. The Harmony Prenatal Test is not for patients with a history of or active malignancy; a pregnancy with fetal demise; a pregnancy with more than two fetuses; or a history of bone marrow or organ transplants.

Patient Pamphlet: https://www.dynacare.ca/DYN/media/DYN/eng/Whats%20Next/Harmony-Brochure-EN-2017DE20.pdf

Cost (Updates as of August 2024):

·         Basic Panel: $349 Trisomy 21 (Down syndrome), Trisomy 18 and 13, and sex chromosome abnormalities (X & Y Chromosomes).

·         Extended Panel: $349 (no extra charge) Basic panel + 22q11.2 deletion syndrome

·         Free ONLY if you have a positive publicly-funded SIPS/IPS/QUAD screen. Funded NIPT collection sites: http://www.perinatalservicesbc.ca/Documents/Screening/Prenatal-HCP/NIPTListFunded.pdf

Syndromes tested: Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome) and Trisomy 13 (Patau syndrome), sex chromosome abnormalities.                                                

Add-On Options: Fetal sex (no charge), 22q11.2 deletion syndrome (no charge)

Where to get it done: Here are a few locations that are most relevant to patients. You can also request the full brochure of locations from admin for Vancouver Coastal Health or Fraser Health when you get your NIPT Requisition.

Vancouver Coastal Health Locations:

  • BC Women’s Hospital (4480 Oak Street, Vancouver)

  • Lions Gate Hospital (231 East 15th Street, North Vancouver)

  • St Paul’s Hospital Laboratory (1081 Burrard Street, Vancouver)

  • UBC Hospital Laboratory (2211 Westbrook Mall, Vancouver)

  • Vancouver General Hospital Outpatient Lab (275 Laurel Street, Vancouver)

Fraser Health Locations:

  • Jim Pattison Outpatient care and Surgery Centre (9750 140th Street, Surrey)

  • Surrey Memorial (13750 96th Avenue, Surrey)

  • Royal Columbian Hospital (330 East Columbia Street, New Westminster)

How early it can be done: >10+0 weeks

Length of time for results: 7-10 business days

Twins: Yes

How to order: Ask your midwives for a requisition. You will also need to print and fill the payment form to accompany your requisition at the lab.

Payment Form

Online Payment Link:

Dynacare Plus Link: https://shop.dynacareplus.com/harmony-non-invasive-prenatal-test-nipt-with-22q11-2-screening-bc.html

Important Notes: Dynacare Plus lists the test as “Harmony NIPT with 22q11.2”. This means there is no extra charge for 22q11.2, but it is not automatically included in the test. If you would like this addition to your test report please let us know so we can mark it off for you. When creating your account please use information that matches the requisition and your government ID, ie. your legal name.

Genetic Counsellor contact: 1-888-988-1888

Accuracy: “Harmony has a less than 0.1% false-positive rate for trisomies 21, 18 and 13. This means fewer than 1 in 1,000 Harmony tests yields a false-positive result.”

Invitae

As of January 22nd, 2024, Invitae was acquired by Natera. As a result, Invitae’s NIPT will no longer be available after February 15th, 2024. Natera’s own NIPT test is Panorama, which is already available in Canada through Life Labs (see above). Please contact your care provider about any questions you may have about this change.